Given how commonly these drugs are prescribed, it is essential to be aware of proton pump inhibitors side effects. PPIs are a group of drugs which are used to treat few of the most common gastric complaints. The most common clinical forms of this drug include Omeprazole, Lansoprazole, Dexlansoprazole, Esomeprazole, Pantoprazole and Rabeprazole. Like all drugs, they have ancillary effects on the human body, some short term and others, long term and more serious.The acids of the stomach perform a dual task. Obviously, they help in the digestive process. They also help in fighting a lot of bacteria as an acidic medium is fatal for most bacteria. However, like everything else associated with the body, there is a delicate balance that needs to be maintained. Sometimes the acid can cause damage such as when there is over-secretion (gastritis, usually stress induced) or if the acid keeps backing up into the esophagus (gastroesophageal reflux). Acids, as we know are corrosive, and thus, in these cases, can cause damage to the stomach lining leading to peptic ulcers or the inflammation of esophageal walls.In short, PPIs are drugs that help regulate the flow of gastric acids into the stomach. By reducing the basic amount of acid flowing in, PPIs reduce the chances of the acid flowing back into the esophagus and also buy more time for the ulcers to heal.Proton pump inhibitors' side effects in the short term are similar to those caused to the body while it is adjusting to most new drugs. Among common complaints are nausea, rashes, fatigue, headaches, dizziness, abdominal pain and diarrhea. Depression and anxiety have been reported, but these are extremely rare cases.
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